HPE
HPE P24466B21 Intel Xeon Gold 5218R 20-core 2.10 GHz server processor
A 20-core Xeon processor with 40 threads, 2.10 GHz base clock, 27.50 MB L3 cache and DDR4-2666 memory support for HPE ProLiant DL380 Gen10 servers
- Integrated Memory Controller SpeedDDR4 2666
- 20 cores and 40 threads accelerate multi-threaded server workloads
- 10 GHz base clock with 4 GHz turbo handles burst demands
- 50 MB L3 cache reduces latency for data-intensive applications
- DDR4 2666 memory controller supports high-speed system memory
- 125 W TDP fits standard server thermal envelopes
Purpose-built server processor
The HPE P24466B21 is a new Intel Xeon Gold 5218R built for HPE ProLiant DL380 Gen10 servers. It delivers 20 cores and 40 threads at a 2.10 GHz base clock with a 4 GHz overclocking speed. The 27.50 MB L3 cache and 14 nm process suit multi-threaded workloads in compatible HPE environments.
Memory controller integration
The integrated DDR4 2666 memory controller removes the need for a separate northbridge component. This direct connection reduces latency between the 20 cores and system memory. The 64-bit processing capability is native to the architecture and requires no extra software to activate.
Socket 3647 thermal envelope
The LGA 3647 package measures 3 inches by 2.2 inches and carries a 125 W thermal design power. The maximum operating temperature is 188.6 °F (87°C), which dictates the server cooling solution required. This processor is validated only for the HPE ProLiant DL380 Gen10 platform.
Highlights
- 20 cores and 40 threads accelerate multi-threaded server workloads
- 10 GHz base clock with 4 GHz turbo handles burst demands
- 50 MB L3 cache reduces latency for data-intensive applications
- DDR4 2666 memory controller supports high-speed system memory
- 125 W TDP fits standard server thermal envelopes
Specifications
| Integrated Memory Controller Speed | DDR4 2666 |
|---|---|
| Shipping weight | 2.27 kg |
| Package size | 292 × 188 × 180 mm |
Questions about this item
Will the 20-core 5218R processor need thermal-paste replacement or fan servicing during its service life?
The processor itself has no moving parts; only the server's heatsink and fans require periodic cleaning or paste renewal per HPE ProLiant DL380 Gen10 maintenance schedules.
What thermal limit is reached first when all 20 cores run at 2.10 GHz continuously?
The CPU throttles at its 87 °C thermal specification, which corresponds to the 125 W TDP ceiling under sustained full-load conditions.
How much heat and fan noise does the 125 W TDP generate inside a DL380 Gen10 running 24/7?
The 125 W TDP is dissipated by the DL380 Gen10's redundant fans; acoustic output and exhaust temperature follow the server's own thermal-profile curves, not the processor alone.
New to this? Buying a processor with crypto — what to check, what it costs to pay, and what is never asked for.
Also in this aisle
People compared these
Same shelf, same checkout — eight coins and a 30-minute rate lock.
minisforum MF-SRP01 SSD Heatsink accessories barebone
- SSD Heatsink
Intel HNS2600BPS24R 2U barebone pc dual Xeon DDR4 2.80 TB C622
- Xeon Bronze Xeon Go…
- DDR4-2933/PC4-23466



